Antibodies to toluene diisocyanate in an environmentally exposed population.
نویسندگان
چکیده
منابع مشابه
Antibodies to toluene diisocyanate in an environmentally exposed population.
Residents living near a polyurethane foam manufacturing facility expressed concern to health officials over chemical emissions from the plant. Environmental monitoring of ambient air near the plant indicated the presence of toluene diisocyanate (TDI), which was used in foam production. Health officials collected blood samples from 113 residents and analyzed the blood sera for antibodies to TDI ...
متن کاملEosinophil infiltration in airways of mice exposed to toluene diisocyanate.
Toluene diisocyanate (TDI) is a chemically reactive low-molecular-weight compound widely used in industries as a polymerizing agent in the production of polyurethanes. TDI has been reported as one of the most important causes of occupational asthma. Clinical investigations have shown that asthma is an inflammatory disorder of the airways and is referred to as chronic eosiniopilic bronchitis . E...
متن کاملEnvironmentally Exposed Population
Residents living near a polyurethane foam manufacturing facility expressed concern to health officials-over chemical emissions from the plnt. Environmental monitoring of ambient air near the plant indicated the presence of toluene diisocyanate (TDI), which was ued in foam producton. Health official collected blood samples from 113 residents and analyzd the blood sera for antibodies to TDI and r...
متن کاملEpithelial folliculin is involved in airway inflammation in workers exposed to toluene diisocyanate
Toluene diisocyanate (TDI) exposure can directly activate and damage airway epithelium. Folliculin (FLCN) is a protein expressed by human airway epithelial cells (HAECs) to maintain airway epithelial integrity and survival. This study investigated the involvement of FLCN in the pathogenesis of TDI-induced occupational asthma (OA). Enzyme-linked immunosorbent assay was used to measure serum leve...
متن کاملMortality of workers exposed to toluene diisocyanate in the polyurethane foam industry.
OBJECTIVE To evaluate cancer mortality among United States workers exposed to toluene diisocyanate (TDI) in the manufacture of polyurethane foam. METHODS This cohort mortality study included 4611 men and women employed in four polyurethane foam plants for at least three months between the late 1950s and 1987. The mortality experience of the cohort was then compared with that of the general Un...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1998
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.98106665